Immigration and labor law reform needed filibuster-proof majorities to pass.
The casualty list from last night's Massachusetts disaster is long and sobering, but I don't think in the end that it will include health-care reform. Any number of Democrats may fear passing the bill for which they've already voted, but the consequences of not passing it will be far worse: a near-total collapse of turnout from the Democratic base in the November elections. (If Barney Frank truly wants to start over, as he suggested last night, then Barney Frank should be primaried.)
Besides, the Democrats don't need 60 Senate votes to complete their job. They need only win a majority in the House for the Senate bill, in conjunction with legislation, passed through the budget reconciliation process that requires just 51 Senate votes, that reflects the compromises on funding and benefits that House and Senate Democrats have already reached.